产品属性:
产品名称 | (1α,1'S,4β)-Lanabecestat |
规格 | 10mM*1mL in DMSO、2mg、5mg、10mg、50mg、100mg、200mg、500mg |
货号 | EY-01Y16776 |
Cas No.: 1384082-96-5
别名: N/A
化学名: N/A
分子式: C26H28N4O
分子量: 412.53
溶解度: DMSO: 250 mg/mL (606.02 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].[1]. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1.
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