上海一研生物科技有限公司

产品属性：

Cas No.: 43119-28-4

别名: N/A

化学名: N/A

分子式: C7H8O2

分子量: 124.1

溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 15 mg/ml

储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

(-)-G-lactone is a bicyclic γ-lactone prostaglandin chiral synthon and a building block.1,2 It is a prostaglandin chiral synthon formed from an asymmetric Baeyer-Villiger oxidation reaction.1 (-)-G-lactone has also been used as a building block in the synthesis of HIV-1 protease inhibitors.21.Alphand, V., Archelas, A., and Furstoss, R.Microbial Transformations 16. One-step synthesis of a pivotal prostaglandin chiral synthon via a highly enantioselective microbiological Baeyer-Villiger type reactionTetrahedron Lett.30(28)3663-3664(1989)

2.Ghosh, A.K., Chapsal, B.D., Baldridge, A., et al.Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P2 ligands: Structure-activity studies and biological evaluationJ. Med. Chem.54(2)622-634(2011)
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