产品属性:
产品名称 | 2-heptyl-3-hydroxy-4(1H)-Quinolone |
规格 | 5mg、10mg |
货号 | EY-01Y16946 |
Cas No.: 108985-27-9
别名: PQS, Pseudomonas Quinolone Signal
化学名: 2-heptyl-3-hydroxy-4(1H)-quinolinone
分子式: C16H21NO2
分子量: 259.3
溶解度: Soluble in methanol
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
2-heptyl-3-hydroxy-4(1H)-Quinolone is a quorum-sensing signaling molecule produced by P. aeruginosa in response to increasing cell density.[1] It increases expression of the lasB gene, which encodes the virulence factor elastase, in P. aeruginosa (EC50 = ~30 µM in a reporter cell assay). 2-heptyl-3-hydroxy-4(1H)-Quinolone (60 µM) increases secretion of the metabolite pyocyanin and the lectin PA-IL, as well as increases biofilm production in P. aeruginosa populations.[2] It also reduces iron levels in P. aeruginosa growth media when used at a concentration of 40 µM and acts as an iron chelator in a Fe(III)-sulfate solution.[3]
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