上海一研生物科技有限公司

产品属性：

Cas No.: N/A

别名: N/A

化学名: N/A

分子式: C22H23ClN6OS

分子量: 454.98

溶解度: Soluble in DMSO

储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

Progesterone receptor membrane component 1 (Pgrmc1) ligand. Inhibits cell cycle progression and cell viability in cancer cell lines. Inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro.Ahmed et al (2010) Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule. J.Pharmacol.Exp.Ther. 333 564 PMID:20164297 |Bashour and Wray (2012) Progesterone directly and rapidly inhibits GnRH neuronal activity via progesterone receptor membrane component 1. Endocrinology. 153 4457 PMID:22822163 |Yoshitani et al (2005) A structure-based strategy for discovery of small ligands binding to functionally unknown proteins: combination of in silico screening and surface plasmon resonance measurements. Proteomics. 5 1472 PMID:15798990
特别提醒公司产品仅供科研使用