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产品属性：
产品名称 | A6770 |
规格 | 500 μg、1 mg、5 mg、10 mg |
货号 | EY-01Y17178 |
Cas No.: 1331754-16-5
别名: N/A
化学名: N/A
分子式: C6H8N2O2
分子量: 140.1
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1 It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50 = <0.01 µM), an effect that is reduced in the presence of vitamin B6 (EC50 = <100 µM). 1.Ohtoyo, M., Tamura, M., Machinaga, N., et al.Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levelsLipids51(10)1207-1216(2016)
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