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产品属性：
产品名称 | 17-phenyl trinor Prostaglandin F2α diethyl amide |
规格 | 1mg、5mg、10mg |
货号 | EY-01Y17213 |
Cas No.: 1176637-26-5
别名: N/A
化学名: N/A
分子式: C27H41NO4
分子量: 443.6
溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
17-phenyl trinor Prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-diethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative PG hypotensive prodrugs. Studies have shown that bovine and human corneal tissue converts the N-ethyl amides of various PGs to the free acids with a conversion efficiency of about 2.5 µg/g corneal tissue/hr. However, dialkyl amides such as 17-phenyl trinor PGF2α diethyl amide are inert to corneal amidase activity, and are not converted in any detectable amount to the corresponding free acids. These compounds may therefore be useful tools in elucidating the claim that PG amides have intrinsic intraocular hypotensive activity.
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