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产品属性：
产品名称 | (Rac)-LM11A-31 dihydrochloride |
规格 | 5mg、10mg、50mg、100mg |
货号 | EY-01Y17319 |
Cas No.: 1214672-15-7
别名: N/A
化学名: N/A
分子式: C12H27Cl2N3O2
分子量: 316.27
溶解度: H2O: ≥ 200 mg/mL (632.37 mM); Ethanol: 100 mg/mL (316.19 mM)
储存条件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist[1].[1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.
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