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产品属性：
产品名称 | Ac-VEID-AMC (ammonium acetate salt) |
规格 | 1 mg、5 mg、10 mg |
货号 | EY-01Y17640 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C32H43N5O11·XC2H7NO2
分子量: 673.7
溶解度: DMSO: 10 mg/ml
储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1 It has also been reported to be cleaved by related proteases, including caspase-8.2 Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.1.Talanian, R.V., Quinlan, C., Trautz, S., et al.Substrate specificities of caspase family proteasesJ. Biol. Chem.272(15)9677-9682(1997)
2.Chae, H.J., Park, K.M., Lee, G.Y., et al.Je-Chun-Jun induced apoptosis of human cervical carcinoma HeLa cellsActa Pharmacologica Sinica25(10)1372-1379(2004)
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