上海一研生物科技有限公司

产品属性：

Cas No.: 483-76-1

别名: N/A

化学名: N/A

分子式: C15H24

分子量: 204.4

溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml

储存条件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

(+)-δ-Cadinene is a sesquiterpene that has been found in upland cotton (G. hirsutum) and has antibacterial, insecticidal, and anticancer activities.1,2,3,4 It is active against S. pneumoniae (MIC = 31.25 µg/ml) and induces mortality in A. stephensi, A. aegypti, and C. quinquefasciatus third instar larvae (LC50s = 8.23, 9.03, and 9.86 µg/ml, respectively).2,3 (+)-δ-Cadinene (10, 50, and 100 µM) induces apoptosis in and inhibits proliferation of OVCAR-3 human ovarian cancer cells.41.Davis, G.D., and Essenberg, M.(+)-δ-Cadinene is a product of sesquiterpene cyclase activity in cottonPhytochemistry39(3)553-567(1995)

2.PÉrez-LÓpez, A., Cirio, A.T., Rivas-Galindo, V.M., et al.Activity against Streptococcus pneumoniae of the essential oil and δ-cadinene isolated from Schinus molle fruitJ. Essent. Oil Res.23(5)25-28(2011)

3.Govindarajan, M., Rajeswary, M., and Benelli, G.δ-Cadinene, calarene and δ-4-carene from Kadsura heteroclita essential oil as novel larvicides against malaria, dengue and filariasis mosquitoesComb. Chem. High Throughput Screen.19(7)565-571(2016)

4.Hui, L.-M., Zhao, G.-D., and Zhao, J.-J.δ-Cadinene inhibits the growth of ovarian cancer cells via caspase-dependent apoptosis and cell cycle arrestInt. J. Clin. Exp. Pathol.8(6)6046-6056(2015)
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