产品属性:
产品名称 | H-Asp-OH |
规格 | 10 mM * 1 mL in Water、1g |
货号 | EY-01Y18074 |
Cas No.: 56-84-8
别名: N/A
化学名: (2S)-2-aminobutanedioic acid
分子式: C4H7NO4
分子量: 133.1
溶解度: Soluble to 100 mM in 1eq. NaOH
储存条件: Store at -20° C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly[1]. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu[2].
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