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产品属性：
产品名称 | Acid Ceramidase-IN-1 |
规格 | 5 mg、10 mg、25 mg |
货号 | EY-01Y18057 |
Cas No.: 2415225-30-6
别名: N/A
化学名: N/A
分子式: C18H25N3O3
分子量: 331.41
溶解度: N/A
储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1].[1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664.
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