产品属性:
产品名称 | (R)-BAY-899 |
规格 | 5 mg、10 mg、25 mg、50 mg |
货号 | EY-01Y18082 |
Cas No.: N/A
别名: N/A
化学名: N/A
分子式: C25H19F2N5O2
分子量: 459.45
溶解度: DMSO : 125 mg/mL (272.06 mM; ultrasonic and warming and heat to 60°C)
储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
(R)-BAY-899 is the R-enantiomer of BAY-899. BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively[1].[1]. Wortmann L, et al. Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels In Vivo. J Med Chem. 2019 Oct 31.
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