上海一研生物科技有限公司

产品属性：

Cas No.: 60842-46-8

别名: N/A

化学名: N/A

分子式: N/A

分子量: 10000.00(Average)

溶解度: H2O: 50 mg/mL

储存条件: 4°C,sealed storage,away from moisture and light
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping Condition:Evaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

FITC-Dextran is a marker consisting of coupling fluorescein-isothiocyanate to dextran. FITC-Dextrans are polysaccharides comprised of varying lengths of branched glucose molecules which available in molecular weights ranging from 4-70 kDa and can be used to determine solute, ion and protein permeability of the blood-brain barrier (BBB) based on the size of the dextran used[1][2][3].[1]. Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15.

[2]. Hoffmann A, et al. High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)-Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations. Transl Stroke Res. 2011 Mar;2(1):106-11.

[3]. Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189.
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