上海一研生物科技有限公司

产品属性：

Cas No.: 112972-60-8

别名: N/A

化学名: N/A

分子式: C18H32N4O6

分子量: 400.5

溶解度: N/A

储存条件: -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping Condition:Evaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

Bisucaberin is a siderophore and bacterial metabolite that has been found in A. haloplanktis and has anticancer activity.1,2 It inhibits the growth of L1210 and 1MC carcinoma cells (IC50s = 9.7 and 12.7 µM, respectively) and sensitizes fibrosarcoma 1023 cells to macrophage-mediated cytolysis. 1.Hou, Z., Raymond, K.N., O’Sullivan, B., et al.A preorganized siderophore: Thermodynamic and structural characterization of alcaligin and bisucaberin, microbial macrocyclic dihydroxamate chelating agentsInorg. Chem.37(26)6630-6637(1998)

2.Kameyama, T., Takahashi, A., Kurasawa, S., et al.Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. I. Taxonomy of the producing organism, isolation and biological propertiesJ. Antibiot. (Tokyo)40(12)1664-1670(1987)
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