上海一研生物科技有限公司

产品属性：

Cas No.: 545-84-6

别名: N/A

化学名: N/A

分子式: C22H28N2O4

分子量: 384.5

溶解度: DMF: 16 mg/ml,DMSO: 16 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml

储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping Condition:Evaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

(-)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 µg/ml). It is cytostatic to wild-type S. cerevisiae and cytotoxic to δrad3-e5 and δrad6-1 mutant S. cerevisiae, which are defective in DNA strand break repair and the mutagenic repair pathway, respectively.
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