上海一研生物科技有限公司

产品属性：

Cas No.: 156223-08-4

别名: N/A

化学名: N/A

分子式: C46H66N8O11

分子量: 907.1

溶解度:

储存条件: -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping Condition:Evaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

产品描述：

Aselacin C is a cyclic pentapeptolide antagonist of endothelin receptor type A (ETA) and ETB originally isolated from Acremonium.1 It inhibits the binding of endothelin-1 to isolated bovine atrial membranes and porcine cerebral membranes, which endogenously express high levels of ETA and ETB, respectively, with IC50 values of 60 and 80 µg/ml, respectively.1.Jackson, M., Burres, N.S., Karwowski, J.P., et al.Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activityJ. Antibiot.47(5)523-527(1994)
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