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产品属性：
产品名称 | Laminaran |
规格 | 100mg、200mg、500mg |
货号 | EY-01Y20099 |
Cas No.: 9008-22-4
别名: N/A
化学名: N/A
分子式: N/A
分子量: N/A
溶解度: DMSO: 100 mg/mL; H2O: 100 mg/mL
储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Laminaran is a neutral water-soluble β-1-3-glucan and a typical ligand for Dectin-1 isolatedfrom the brown alga D. dichotoma, has potent immunomodulating, radioprotective, and anticancer activities[1]. Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds[2]. Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy[3].[1]. Malyarenko OS, et al. Laminaran from brown alga Dictyota dichotoma and its sulfated derivative as radioprotectors and radiosensitizers in melanoma therapy.Carbohydr Polym. 2019 Feb 15;206:539-547.
[2]. Laminaran
[3]. Song K, et al. Laminarin promotes anti-cancer immunity by the maturation of dendritic cells.Oncotarget. 2017 Jun 13;8(24):38554-38567.
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