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产品属性：
产品名称 | Ferutinin |
规格 | 1mg、5mg、10mg |
货号 | EY-01Y20338 |
Cas No.: 41743-44-6
别名: N/A
化学名: 4-hydroxy-benzoic acid, (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester
分子式: C22H30O4
分子量: 358.5
溶解度: Soluble in DMSO
储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM). It also demonstrates ionophoretic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes at a concentration range of 1-50 uM. Ferutinin is cytotoxic to MCF-7 breast and TCC bladder cancer cells as well as human foreskin HFF3 fibroblasts (IC50s = 29, 24, and 36 ug/ml in vitro after 72 hours of exposure).
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