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产品属性：
产品名称 | Rhein-8-glucoside |
规格 | 1mg、5mg、10mg、25mg |
货号 | EY-01Y20497 |
Cas No.: 34298-86-7
别名: N/A
化学名: N/A
分子式: C21H18O11
分子量: 446.4
溶解度: DMSO: slightly soluble
储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
Rhein-8-glucoside is an anthraquinone glycoside that has been found in rhubarb.1 It increases the rate of sennoside A metabolism by mouse intestinal bacteria in vitro when used at concentrations ranging from 0.03 to 1 mM. Rhein-8-glucoside increases the purgative activity of sennoside A in mice in a dose-dependent manner. It also inhibits human protein tyrosine phosphatase (PTP1B; IC50 = 11.5 μM).2 Rhein-8-glucoside is metabolized to rhein by intestinal bacteria.1|1. Takayama, K., Tsutsumi, H., Ishizu, T., et al. The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice. Biol. Pharm. Bull. 35(12), 2204-2208 (2012).|2. Li, S., An, T.-Y., Li, J., et al. PTP1B inhibitors from Saussrurea lappa. J. Asian Nat. Prod. Res. 8(3), 281-286 (2006).
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