产品属性:
产品名称 | (+)-Oxanthromicin |
规格 | 250μg、1mg |
货号 | EY-01Y20667 |
Cas No.: 1616622-08-2
别名: N/A
化学名: (10R)-10,10'R-dioxybis[9,10-dihydro-3,8-dihydroxy-1,7,10-trimethyl-9-oxo-2-anthracenecarboxylic acid]
分子式: C36H30O12
分子量: 654.6
溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
(+)-Oxanthromicin is an enantiomer of the rare Streptomyces metabolite (-)-oxanthromicin. [1] It inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 62.5 μM.
Referene:[1]. Salim, A.A., Xiao, X., Cho, K.-J., et al. Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Org. Biomol. Chem. 12(27), 4872-4878 (2014).
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